Jul 04

An irreversible, progressive brain disease affecting millions worldwide, Alzheimers disease is devastating for its victims, robbing them of their memory and cognitive skills and ultimately of their lives. Even after decades of research, however, the causes of AD remain elusive. Two features in the brain, abnormal clumps (senile plaques) and tangled bundles of fibers (neurofibrillary tangles), are known to characterize AD, but there is little consensus on the link between these features and the underlying roots of the disease.

One hypothesis that has attracted widespread support proposes that AD is caused by the buildup of the senile plaques, and in particular of their main constituent, amyloid- peptides (A).

Tags: , Disease

Jun 01

Scientists have come a step closer to finding out what the causes of Alzheimers disease are.

Recently the number of genes known to be associated with Alzheimers disease has increased from four to eight, including the MS4A gene cluster on chromosome 11.

New research has expanded on this using a genome-wide association study (GWAS) to find a novel location within the MS4A gene cluster, which is associated with Alzheimers disease.

Alzheimers disease is the most common cause of dementia in the developed world.

Tags: , Disease

Feb 24

FRIDAY, Feb. 25 () — Most patients struggling with a progressive and fatal form of lung disease called idiopathic pulmonary fibrosis do not risk a worsening of their condition as a result of exposure to a viral infection, new research indicates.

The finding contradicts prior investigations that had suggested viral infections might rapidly advance disease in patients diagnosed with idiopathic pulmonary fibrosis (IPF).

“The results of this study suggest that the majority of cases of acute exacerbation of IPF are not due to viral infection,” study author Dr.

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Tags: Disease , Lung Disease