Mar 27

One in nine HIV-infected children with advanced illness was hospitalised with severe malnutrition within 12 weeks of starting antiretroviral and these children had a 15-fold increased risk of dying within the first six months compared to those children not hospitalised, Andrew Prendergast and colleagues reported in the ARROW study published in the advance online edition of AIDS.

The high frequency of new cases of severe malnutrition in children after starting antiretroviral therapy (ART) is not easy to explain say the researchers, and they warn that health care workers need to be alert for the condition, especially in children who are already malnourished.

Treatment programmes for children also need to integrate HIV and malnutrition care, and look at whether nutritional supplementation before starting treatment can protect against development of severe malnutrition once ART begins.

Antiretroviral Research for Watoto (ARROW) is an open-label, randomised trial of induction-maintenance and monitoring strategies for antiretroviral treatment in 1207 HIV-infected children with a median age of 6 (3-17) in three hospitals in Uganda and one in Zimbabwe recruited from March 2007 to November 2008.

HIV infection and malnutrition among children in resource-limited settings cannot be separated.

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Mar 26

FRIDAY, March 25 () — The drug Yervoy (ipilimumab) has been approved by the U.S. Food and Drug Administration to treat late-stage melanoma, the deadliest form of skin cancer.

Citing statistics from the National Cancer Institute, the FDA said some 68,130 cases of melanoma were diagnosed in the United States last year, and about 8,700 people died from it.

Yervoy appears to block a molecule called CTLA-4 that is believed to slow or disable the immune system, hindering the body’s ability to fight cancer, the FDA said in a news release.

The intravenous drug was evaluated in clinical studies of 676 people with melanoma.

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Tags: Melanoma

Mar 26

A new study has found that drinking four to six mugs of tea daily is as good as a litre of water for keeping yourself hydrated.

The finding disproves the idea that regular tea drinking can dehydrate the body because of its caffeine content.

The research also found no negative health effects from drinking that amount of tea.

In the high quality UK clinical trial, 21 volunteers drank either four 240ml mugs of tea over a 12-hour period equivalent to just under one litre of tea in total or a similar amount of plain, boiled water served warm.

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Mar 25

After age 21, problem gambling is considerably more common among U.S. adults than alcohol dependence, even though alcohol dependence has received much more attention, according to researchers at the University at Buffalo’s Research Institute on Addictions.

In results published this month in the Journal of Gambling Studies, John W. Welte, principal investigator on the study and a national expert on alcohol and gambling pathology, concluded that there is a distinct inconsistency between his research and much of the other research literature. Other research supports the proposition that problem gambling is more common among adolescents than among adults. Problem gambling has often been described as rare. E

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